Release 55
(Dec 23, 2024)

Whole genome analysis for QTL/association enrichment

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Version: Enrich S: beta v0.8
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Data:

Number of limb traits traits:19
Number of QTL / associations found:3,091
Number of chromosomes where QTL / associations are found:30

Chi-squared (χ2) test: are limb traits traits over-represented on some chromosomes?

Chromosomes Total χ2 df p-values FDR * Size of χ2
Chromosome X2698.40584299e-411.687500e-40
Chromosome 11064.19684292.296971e-2053.445456e-204
Chromosome 2309.48321291.076857e-482.485055e-48
Chromosome 31.62298290.9983293258231159.983293e-01
Chromosome 4144.91908292.32792e-173.675663e-17
Chromosome 5754.54187293.894473e-1401.947237e-139
Chromosome 6479.01413295.831977e-831.749593e-82
Chromosome 7165.59716294.436027e-217.393378e-21
Chromosome 8115.56142292.751095e-123.930136e-12
Chromosome 941.67612290.060033777.830492e-02
Chromosome 1089.52325294.309631e-085.876770e-08
Chromosome 111955.10076299e-411.687500e-40
Chromosome 12310.49135296.794825e-491.698706e-48
Chromosome 131806.14969299e-411.687500e-40
Chromosome 1422.17813290.81273979.030441e-01
Chromosome 15853.53111296.547707e-1616.547707e-160
Chromosome 1631.32473290.35027864.041676e-01
Chromosome 17356.47002294.492114e-581.225122e-57
Chromosome 182.99991290.9983293258231159.983293e-01
Chromosome 19134.76434291.423499e-152.135249e-15
Chromosome 202.90149290.9983293258231159.983293e-01
Chromosome 2136.31603290.16453851.974462e-01
Chromosome 22226.32819291.860589e-323.283392e-32
Chromosome 23480.26813293.226819e-831.075606e-82
Chromosome 24642.64403298.921344e-1173.823433e-116
Chromosome 251066.06549299.239521e-2062.771856e-204
Chromosome 2641.30714290.064725468.090683e-02
Chromosome 27480.26813293.226819e-831.075606e-82
Chromosome 28779.91618291.878833e-1451.127300e-144
Chromosome 29828.62401291.125607e-1558.442053e-155

Chi-squared (χ2) test: Which of the 19 limb traits traits are over-represented in the QTLdb

Traits Total χ2 df p-values FDR * Size of χ2
Digital cushion thickness 330.1107 18 2.980756e-59 5.663436e-58
Digital dermatitis 138.81365 18 1.083909e-20 5.148568e-20
Feet and leg conformation 44.91562 18 0.0004262024 5.398564e-04
Foot angle 38.97483 18 0.002871907 3.209778e-03
Foot diagonal 69.25001 18 6.050407e-08 8.211267e-08
Heel depth 35.31879 18 0.008616021 9.094689e-03
Heel horn erosion 100.38884 18 1.879824e-13 3.968517e-13
Hind leg conformation 40.93058 18 0.001556310 1.848118e-03
Hoof and leg disorders 160.18159 18 7.677227e-25 4.862244e-24
Hoof trimming status 87.3143 18 4.367327e-11 8.297921e-11
Interdigital dermatitis 117.54907 18 1.215603e-16 3.299494e-16
Interdigital hyperplasia 108.68844 18 5.519886e-15 1.310973e-14
Laminitis 28.53795 18 0.05432668 5.432668e-02
Rear leg placement - rear view 80.25821 18 7.722273e-10 1.128640e-09
Rear leg placement - side view 86.2998 18 6.621897e-11 1.143782e-10
Sole hemorrhage 125.03395 18 4.677681e-18 1.481266e-17
Sole ulcer 166.40826 18 4.611589e-26 4.381010e-25
Toe ulcer 132.5944 18 1.693545e-19 6.435471e-19
White line disease 85.60827 18 8.789061e-11 1.391601e-10

Correlations found between some of these traits for your reference

No correlation data found on these traits

Overall Test

Data Chi'Square Test Fisher's Exact Test
Number of chrom.:30 χ2=15922.190760
Number of traits:19 df=522
Number of QTLs:3,091 p-value=0

FOOT NOTE: * : FDR is short for "false discovery rate", representing the expected proportion of type I errors. A type I error is where you incorrectly reject the null hypothesis, i.e. you get a false positive. It's statistical definition is FDR = E(V/R | R > 0) P(R > 0), where V = Number of Type I errors (false positives); R = Number of rejected hypotheses. Benjamini–Hochberg procedure is a practical way to estimate FDR.

 

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