| QTL Map Information |
|---|
| Chromosome: | 11 |
| QTL Peak Location: | 93.23 (cM) |
| QTL Span: | 92.62-93.83 (cM)
77.2-78.2 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | rs29018852 |
| Peak: | |
| Lower, "Significant": | rs109947132 |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | QTL |
| Model tested: | Mendelian |
| Test base: | Genome-wise |
| Threshold significance level: | Significant |
 |
P_values | <0.05 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | n/a |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
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| QTL Experiment in Brief |
|---|
| Animals: | Animals were Holstein cattle. |
| Breeds associated:
|
| Design: | Animals were genotyped using the Illumina BovineSNP50 v2 BeadChip and analyzed for incidence of pronounced hypocholesterolemia. A total of 44,747 SNPs were used for analysis. |
| Analysis: | A case-control study and mixed model analyses were used. |
| Software: | Beagle, GCTA, R software |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Kipp S, Segelke D, Schierenbeck S, Reinhardt F, Reents R, Wurmser C, Pausch H, Fries R, Thaller G, Tetens J, Pott J, Haas D, Raddatz B B, Hewicker-Trautwein M, Proios I, Schmicke M, Grünberg W |
| Affiliation: | Clinic for Cattle, University of Veterinary Medicine Hannover, Foundation, Bischofsholer Damm 15, 30173 Hanover, Germany |
| Title: | Identification of a haplotype associated with cholesterol deficiency and increased juvenile mortality in Holstein cattle |
| Journal: | Journal of dairy science, 2016, 99(11): 8915-8931 |
| Links: |
PubMed | Abstract | List all data
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