Release 56
(Apr 24, 2025)

QTL 314680 Description:

 Trait Information
Trait name: M. paratuberculosis susceptibility Vertebrate Trait Ontology: n/a
Trait details: multifocal histological lesions Product Trait Ontology: n/a
Symbol: MPARA Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:22
QTL Peak Location:n/a
QTL Span:n/a
3.1-3.1 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs137711821
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:QTL
Model tested:n/a
Test base:Comparison-wise
Threshold significance level:Significant
P_values8.62E-10
Dominance effect:n/a
Additive effect:n/a
Associated Gene:n/a
Cis/Trans acting type:
Links:   Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Spanish Holstein cows.
     Breeds associated:
    Design:Animals were genotyped using the EuroG MD BeadChip, with data imputed to HD then whole-genome sequence, and GWAS were performed for the presence or absence of bovine paratuberculosis lesions. A total of 13,881,067 SNSPs were used for analysis.
    Analysis:Mixed linear models were used.
    Software:GCTA 1.93.2, Eagle 2.4, minimac4
    Notes: 
    Links:Edit

     Reference
    Authors:Canive M, Badia-Bringué G, Vázquez P, González-Recio O, Fernández A, Garrido JM, Juste RA, Alonso-Hearn M
    Affiliation:Department of Animal Health, NEIKER-Basque Institute for Agricultural Research and Development, Basque Research and Technology Alliance (BRTA), Derio, Bizkaia, Spain
    Title:Identification of loci associated with pathological outcomes in Holstein cattle infected with Mycobacterium avium subsp. paratuberculosis using whole-genome sequence data
    Journal:Scientific reports, 2021, 11(1): 20177
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #34635747
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  • Cite this Data:

    Animal QTLdb: QTL314680 was published in 2021, and was curated into QTLdb on 2025-03-06. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:314680

     

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