Release 56
(Apr 24, 2025)

QTL 17340 Description:

 Trait Information
Trait name: Marek's disease susceptibility Vertebrate Trait Ontology: n/a
Reported name: Marek's disease-related traits Product Trait Ontology: n/a
Symbol: MD Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:1
QTL Peak Location:449.4 (cM)
QTL Span:0.00-100.00 (cM)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:
Analysis type:Association
Model tested:Mendelian
Test base:n/a
Threshold significance level:Significant
P_values<0.05
Dominance effect:n/a
Additive effect:n/a
Associated Gene:IRG1 (immunoresponsive 1 homolog (mouse))
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Birds were from a cross between Marek's Disease–resistant and –susceptible White Leghorn inbred lines.
     Breeds associated:
    Design:Birds were genotyped for six SNPs in five genes and analyzed for susceptibility to Marek's Disease.
    Analysis:REML, ANOVA, and chi-square analyses were used.
    Software: 
    Notes: 
    Links:Edit

     Reference
    Authors:Smith J, Sadeyen JR, Paton IR, Hocking PM, Salmon N, Fife M, Nair V, Burt DW, Kaiser P
    Affiliation:The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, United Kingdom
    Title:Systems analysis of immune responses in Marek's disease virus-infected chickens identifies a gene involved in susceptibility and highlights a possible novel pathogenicity mechanism.
    Journal:Journal of virology, 2011, 85(21): 11146-58
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #21865384
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  • Cite this Data:

    Animal QTLdb: QTL17340 was published in 2011, and was curated into QTLdb on 2012-06-21. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:17340

     

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