Release 56
(Apr 24, 2025)

QTL 263591 Description:

 Trait Information
Trait name: Marek's disease susceptibility Vertebrate Trait Ontology: n/a
Reported name: (n/a) Product Trait Ontology: n/a
Symbol: MD Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:Z
QTL Peak Location:n/a
QTL Span:n/a
Upper, "Suggestive":n/a
Upper, "Significant":rs318133768
Peak:
Lower, "Significant":rs314585413
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:QTL
Model tested:n/a
Test base:n/a
Threshold significance level:Significant
P_values<0.01
Dominance effect:n/a
Additive effect:n/a
Associated Gene:n/a
Cis/Trans acting type:
Links:   Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Chickens either from a full-sib advanced intercross line used to map QTLRs affecting MD resistance produced by intercrossing two White Leghorn lines (F6), or from eight elite commercial egg production lines representing White Leghorn, White Plymouth Rock, and Rhode Island Red.
     Breeds associated:
    Design:Birds were genotyped using the Affymetrix 600K chicken SNP array, and markers on GGZ were analyzed for association with Marek's Disease susceptibility.
    Analysis:In the F6 population, QTLRs were mapped using the JMP SNP-trait association trend test. For the eight elite lines, males with high or low daughter MD mortality were selected and used to create DNA pools, and QTLs were identified within lines.
    Software:JMP Genomics
    Notes: 
    Links:Edit

     Reference
    Authors:Lipkin E, Smith J, Soller M, Burt DW, Fulton JE
    Affiliation:Department of Genetics, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem 91904, Israel
    Title:Sex Differences in Response to Marek's Disease: Mapping Quantitative Trait Loci Regions (QTLRs) to the Z Chromosome
    Journal:Genes, 2022, 14(1):20
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:F6 population, family 2
    User inputs on reference #36672761
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  • Cite this Data:

    Animal QTLdb: QTL263591 was published in 2022, and was curated into QTLdb on 2023-02-22. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:263591

     

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