Release 56
(Apr 24, 2025)

This linkage-map based data has been obsolete
(see Release notes 51, 52, 53). Information
provided here is only for retrospective online
support of publications that used this data.

QTL 4596 Description:

 Trait Information
Trait name: Marek's disease susceptibility Vertebrate Trait Ontology: n/a
Reported name: Marek's disease-related traits Product Trait Ontology: n/a
Symbol: MD Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:4
QTL Peak Location:50.00 (cM)
QTL Span:162-169 (cM)
54.6-56.9 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":UMA4027
Peak:
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:
Analysis type:QTL
Model tested:n/a
Test base:n/a
Threshold significance level:n/a
P_values<0.048
Dominance effect:n/a
Additive effect:-4.69
Associated Gene:APP (amyloid beta (A4) precursor protein)
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

User inputs on QTL #4596
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  •  QTL Experiment in Brief
    Animals:A full-sib intercross population was generated by crossing two partially inbred commercial White Leghorn lines differing in genetic resistance to Marek's Disease.
     Breeds associated:
    n/a
    Design:DNA pools were genotyped for 15 SNPs and 217 microsatellite markers, and post-challenge survival time was determined.
    Analysis:A variety of statistical tests were used, including Z-test, Chi-square, interval analysis, ANOVA, and nonparametric sign test.
    Software:Excel, JMP 5.1.2
    Notes: 
    Links:Edit

     Reference
    Authors:Heifetz, E M; Fulton, J E; O'Sullivan, N P; Arthur, J A; Cheng, H; Wang, J; Soller, M; Dekkers, J C M
    Affiliation:Iowa State University, Ames, IA, USA; Ariel University, Ariel, Israel; Hy-Line International, Dallas Center, IA, USA; USDA-ARS-ADOL, East Lansing, MI, USA; Pioneer Hi-Bred International Inc., Johnston, IA, USA; The Hebrew University,
    Title:Mapping QTL affecting resistance to Marek's disease in an F6 advanced intercross population of commercial layer chickens
    Journal:BMC Genomics, 2009, 10:20
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:Significant by chi-square
    User inputs on reference #19144166
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  • Cite this Data:

    Animal QTLdb: QTL4596 was published in 2009, and was curated into QTLdb on 2009-03-11. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:4596

     

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