Release 56
(Apr 24, 2025)

QTL 9273 Description:

 Trait Information
Trait name: Marek's disease susceptibility Vertebrate Trait Ontology: n/a
Reported name: Marek's disease-related traits Product Trait Ontology: n/a
Symbol: MD Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:27
QTL Peak Location:25 (cM)
QTL Span:0.00-100.00 (cM)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:GH1
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:Microsatellites
Analysis type:Association
Model tested:Mendelian
Test base:n/a
Threshold significance level:Significant
P_values0.01
Dominance effect:n/a
Additive effect:n/a
Associated Gene:GH (growth hormone)
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were from a cross between two commercial White Leghorn lines.
     Breeds associated:
    Design:Birds were analyzed for GH1 genotype and examined for response to Marek's disease virus infection.
    Analysis:ANOVA and chi-square analyses were used in association studies.
    Software:JMP
    Notes: 
    Links:Edit

     Reference
    Authors:Liu, H C; Kung, H J; Fulton, J E; Morgan, R W; Cheng, H H
    Affiliation:U.S. Department of Agriculture, Agricultural Research Service, Avian Disease and Oncology Laboratory, East Lansing, MI 48823, USA
    Title:Growth hormone interacts with the Marek's disease virus SORF2 protein and is associated with disease resistance in chicken.
    Journal:Proceedings of the National Academy of Sciences of the United States of America, 2001, 98 (16): 9203-8
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:Number of tissues with tumors
    User inputs on reference #11470922
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  • Cite this Data:

    Animal QTLdb: QTL9273 was published in 2001, and was curated into QTLdb on 2009-10-20. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:9273

     

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