Release 56
(Apr 24, 2025)

Reference # 32910467 Details:

Authors:Pasandideh M, Gholizadeh M, Rahimi-Mianji G (Contact: majidpasandideh@gmail.com)
Affiliation:Department of Animal Science, Faculty of Animal and Aquatic Sciences, Sari Agricultural Sciences and Natural Resources University, PO Box 578, Sari, Iran
Title:A genome-wide association study revealed five SNPs affecting 8-month weight in sheep
Journal:Animal Genetics, 2020, 51(6): 973-976 DOI: 10.1111/age.12996
Abstract:

Lamb weight at 8 months of age is an important trait in the sheep industry in terms of the onset of puberty around this age; however, knowledge of its effective genetic factors is limited. Therefore, a GWAS using the 50K SNP-Chip was performed on 96 Baluchi sheep to identify the genomic regions associated with 8-month weight. The results of the present study revealed five SNPs on chromosomes 4, 14 and 16 at 5% chromosome-wide significance level, jointly accounting for 0.95% of total genetic variance. Four genes - MTPN, HYDIN, LRGUK and ZFP90 - were found in 50 kb intervals around the significant SNPs, of which MTPN is involved in regulation of skeletal muscle growth. Our results may provide a new vision to identify the genomic regions affecting growth traits in sheep.

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