| QTL Map Information |
|---|
| Chromosome: | 1 |
| QTL Peak Location: | 277.58 (cM) |
| QTL Span: | 277.58-277.58 (cM)
235.1-235.1 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | rs419889303 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | Association |
| Model tested: | Mendelian |
| Test base: | Genome-wise |
| Threshold significance level: | Significant |
 |
Fst | 0.468 | | P_values | 0.03123 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | CLRN1 (clarin 1) |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
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| QTL Experiment in Brief |
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| Animals: | Animals were Valle del Belice sheep. |
| Breeds associated:
|
| Design: | Animals were genotyped using the Illumina OvineSNP50 BeadChip and analyzed for incidence of microtia. A total of 45,836 autosomal SNPs were used for analysis. |
| Analysis: | GWAS was carried out using a univariate case-control model. Fisher's exact test and an F(ST) case-control analysis were also used. |
| Software: | PLINK, SNPASSOC in R |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Mastrangelo S, Sottile G, Sutera A M, Di Gerlando R, Tolone M, Moscarelli A, Sardina M T, Portolano B |
| Affiliation: | Dipartimento Scienze Agrarie, Alimentari e Forestali, University of Palermo, 90128, Palermo, Italy |
| Title: | Genome-wide association study reveals the locus responsible for microtia in Valle del Belice sheep breed |
| Journal: | Animal genetics, 2018, 49(6): 636-640 |
| Links: |
PubMed | Abstract | List all data
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