Release 56
(Apr 24, 2025)

QTL 211735 Description:

 Trait Information
Trait name: Entropion Vertebrate Trait Ontology: n/a
Reported name: (n/a) Product Trait Ontology: n/a
Symbol: ENTR Clinical Measurement Ontology: n/a
 QTL Map Information
Chromosome:6
QTL Peak Location:139.28 (cM)
QTL Span:139.28-139.28 (cM)
104.6-104.6 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs424438792
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:Association
Model tested:Mendelian
Test base:Genome-wise
Threshold significance level:Significant
P_values0.007
Dominance effect:n/a
Additive effect:n/a
Associated Gene:SLC2A9 (solute carrier family 2 member 9)
Cis/Trans acting type:
Links:   Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Columbia, Polypay, and Rambouillet sheep.
     Breeds associated:
    Design:Animals were genotyped using the Illumina OVineSNP50 Infinium BeadChip and analyzed for congenital entropion.
    Analysis:Logistic regression methods were used, with an additional step to assess fit for additive allelic, recessive, dominant, and genotypic inheritance models.
    Software:PLINK, SAS
    Notes: 
    Links:Edit

     Reference
    Authors:Mousel MR, Reynolds JO, White SN
    Affiliation:Animal Disease Research Unit, Agricultural Research Service, Department of Agriculture, Pullman, WA, United States of America; Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, United States of America
    Title:Genome-Wide Association Identifies SLC2A9 and NLN Gene Regions as Associated with Entropion in Domestic Sheep
    Journal:PloS one, 2016, 10(6): e0128909
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #26098909
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  • Cite this Data:

    Animal QTLdb: QTL211735 was published in 2016, and was curated into QTLdb on 2020-06-03. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:211735

     

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