QTL Map Information |
Chromosome: | 1 |
QTL Peak Location: | 293.04 (cM) |
QTL Span: | 293.04-293.04 (cM) 248.2-248.2 (Mbp) |
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Upper, "Suggestive": | n/a |
Upper, "Significant": | n/a |
Peak: | rs420083564 |
Lower, "Significant": | n/a |
Lower, "Suggestive": | n/a |
Marker type: | SNP |
Analysis type: | Association |
Model tested: | Mendelian |
Test base: | Comparison-wise |
Threshold significance level: | Significant |
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P_values | 2.22E-6 | Dominance effect: | n/a |
Additive effect: | n/a |
Associated Gene: | PIK3CB (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta) |
Cis/Trans acting type: |  |
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Extended information: |
(none) |
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QTL Experiment in Brief |
Animals: | Animals were Columbia, Polypay, and Rambouillet sheep. |
Breeds associated:
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Design: | Animals were genotyped using the Illumina OVineSNP50 Infinium BeadChip and analyzed for congenital entropion. |
Analysis: | Logistic regression methods were used, with an additional step to assess fit for additive allelic, recessive, dominant, and genotypic inheritance models. |
Software: | PLINK, SAS |
Notes: | |
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Reference |
Authors: | Mousel MR, Reynolds JO, White SN |
Affiliation: | Animal Disease Research Unit, Agricultural Research Service, Department of Agriculture, Pullman, WA, United States of America; Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, United States of America |
Title: | Genome-Wide Association Identifies SLC2A9 and NLN Gene Regions as Associated with Entropion in Domestic Sheep |
Journal: | PloS one, 2016, 10(6): e0128909 |
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PubMed | Abstract | List all data
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