| QTL Map Information |
|---|
| Chromosome: | 15 |
| QTL Peak Location: | n/a |
| QTL Span: | n/a
48.0-48.0 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | rs430842113 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | Association |
| Model tested: | n/a |
| Test base: | Genome-wise |
| Threshold significance level: | Significant |
 |
P_values | <0.05 | | Dominance effect: | 0.14 |
| Additive effect: | n/a |
| Associated Gene: | n/a |
| Cis/Trans acting type: |  |
| Links:
Edit |
Map view
|
| Extended information: |
|---|
| (none) |
User inputs on QTL #239964
Add your annotations
Add your comments
Report problems
|
| QTL Experiment in Brief |
|---|
| Animals: | Animals were Romney, Coopworth, and Perendale sheep, or a composite of these breeds. |
| Breeds associated:
|
| Design: | Animals were genotyped using either the Illumina OvineSNP50 BeadChip (with data imputed to HD) or the Ovine Infinium HD SNP BeadChip, and GWAS was performed for susceptibility to facial eczema, determined by serum concentration of the enzyme gamma-glutamyltransferase 21 days after sporidesmin challenge. A total of 481,400 SNPs were used for analysis. |
| Analysis: | Two methods were used for GWAS: 1) an Efficient Mixed-Model Association eXpedited (EMMAX) analysis using a kinship matrix was performed on log-transformed serum GGT levels, and 2) genotype association tests were performed on the residuals obtained from ASReml after fitting recorded pedigree and the fixed effect of the contemporary group. |
| Software: | FImpute, SVS v8.4.0, ASReml |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | McRae KM, Rowe SJ, Johnson PL, Baird HJ, Cullen NG, Bixley MJ, Plowman JE, Deb-Choudhury S, Brauning R, Amyes NC, Dodds KG, Newman SN, McEwan JC, Clarke SM |
| Affiliation: | AgResearch Limited, Invermay Agricultural Centre, Puddle Alley, Mosgiel, Private Bag 50034, New Zealand |
| Title: | Genomic Tools for the Identification of Loci Associated with Facial Eczema in New Zealand Sheep |
| Journal: | Genes, 2021, 12(10) |
| Links: |
PubMed | Abstract | List all data
| Edit |
User inputs on reference #34680955
Add your comments
Note similar findings
Note contradictions
|
