Release 56
(Apr 24, 2025)

QTL 24086 Description:

 Trait Information
Trait name: HDL cholesterol Vertebrate Trait Ontology: Blood HDL cholesterol amount
Reported name: HDL cholesterol Product Trait Ontology: n/a
Symbol: HDL Clinical Measurement Ontology: Blood high density lipoprotein cholesterol level
 QTL Map Information
Chromosome:4
QTL Peak Location:13.6 (cM)
QTL Span:7.16-7.25 (cM)
5.4-5.5 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:
Analysis type:Association
Model tested:Mendelian
Test base:Comparison-wise
Threshold significance level:Significant
P_values0.003
Dominance effect:n/a
Additive effect:n/a
Associated Gene:TRIB1 (tribbles homolog 1 (Drosophila))
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Duroc pigs.
     Breeds associated:
    Design:A previously identified QTL region for serum triglyceride level was refined by genotyping for four additional microsatellites. Animals were also genotyped for polymorphisms in LRP12 and TRIB1 and analyzed for serum and muscle lipid traits.
    Analysis:QTL analyses were performed using a regression approach. LRP12 and TRIB1 association analyses were carried out with PROC GLM.
    Software:CRIMAP, QTL Express, SAS
    Notes: 
    Links:Edit

     Reference
    Authors:Melo C, Quintanilla R, Gallardo D, Zidi A, Jordana J, Díaz I, Pena R N, Amills M
    Affiliation:Department of Animal Genetics, Center for Research in Agricultural Genomics (CSIC-IRTA-UAB-UB), Universitat Autònoma de Barcelona, Bellaterra, 08193 Spain.
    Title:Association analysis with lipid traits of 2 candidate genes (LRP12 and TRIB1) mapping to a SSC4 QTL for serum triglyceride concentration in pigs
    Journal:Journal of animal science, 2013, 91(4): 1531-7
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:c.*156_157del
    User inputs on reference #23408821
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  • Cite this Data:

    Animal QTLdb: QTL24086 was published in 2013, and was curated into QTLdb on 2014-02-07. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:24086

     

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