Release 56
(Apr 24, 2025)

This linkage-map based data has been obsolete
(see Release notes 51, 52, 53). Information
provided here is only for retrospective online
support of publications that used this data.

QTL 12902 Description:

 Trait Information
Trait name: Immunoglobulin G level Vertebrate Trait Ontology: Blood immunoglobulin G amount
Reported name: Trichostrongylus colubriformis serum IgG challenge 2 Product Trait Ontology: n/a
Symbol: IGG Clinical Measurement Ontology: Serum immunoglobulin G level
 QTL Map Information
Chromosome:23
QTL Peak Location:30.9 (cM)
QTL Span:21.9-42.7 (cM)
16.3-31.8 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":MCMA1
Peak:30.9
Lower, "Significant":ADCY1AP
Lower, "Suggestive":n/a
Marker type:Microsatellites
Analysis type:QTL
Model tested:n/a
Test base:n/a
Threshold significance level:n/a
F_Stat14
Dominance effect:n/a
Additive effect:n/a
Associated Gene:n/a
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

User inputs on QTL #12902
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  •  QTL Experiment in Brief
    Animals:940 lambs from 5 half-sib families;selective genotyping (22 top, 22 bottom per sire); genome screen 203 microsatellites; all offspring then genotyped for chromosomes 1, 3, 4, 5, 8, 12, 13, 22 and 23
     Breeds associated:
    n/a
    Design:outcross; 2 natural pasture challenges
    Analysis:worm counts and fecs log transformed (ln(x+c) where x=count and c=unit count); Nematodirus counts scaled to average s.d. after log transformation total IgE log transformed least squares interval mapping - Haley-Knott regression
    Software: 
    Notes: 
    Links:Edit

     Reference
    Authors:Crawford AM,Paterson KA, Dodds KG, Diez Tascon C, Williamson PA, Roberts Thomson M, Bisset SA, Beattie AE, Greer GJ, Green RS, W
    Affiliation:AgResearch, Invermay Agricultural Centre, Private Bag 50034, Mosgiel, New Zealand. allan.crawford@agresearch.co.nz
    Title:Discovery of quantitative trait loci for resistance to parasitic nematode infection in sheep: I. Analysis of outcross pedigrees.
    Journal:BMC Genomics, 2006, 7:178
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:T. colubriformus IgG 4 weeks into second field challenge; single sire 92/0154 348 progeny; effect size 0.07 ± 0.02
    User inputs on reference #16846521
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  • Cite this Data:

    Animal QTLdb: QTL12902 was published in 2006, and was curated into QTLdb on 2007-05-10. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:12902

     

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