| QTL Map Information |
|---|
| Chromosome: | 13 |
| QTL Peak Location: | 87.1 (cM) |
| QTL Span: | 93.04-93.24 (cM)
60.6-60.7 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | |
| Analysis type: | Association |
| Model tested: | Mendelian |
| Test base: | n/a |
| Threshold significance level: | Significant |
 |
P_values | <0.05 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | PRNP (prion protein) |
| Cis/Trans acting type: |  |
| Links:
NCBI GeneDB | Edit |
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|
| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
|---|
| Animals: | Animals were Cheviot sheep. |
| Breeds associated:
|
| Design: | Animals were genotyped for polymorphisms in PRNP and analyzed for susceptibility to bovine spongiform encephalopathy. |
| Analysis: | Sheep were challenged by intravenous inoculation with BSE and monitored for disease status. |
| Software: | |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Goldmann W, Houston F, Stewart P, Perucchini M, Foster J, Hunter N |
| Affiliation: | Institute for Animal Health (IAH), Neuropathogenesis Unit, West Mains Road, Edinburgh EH9 3JF, UK |
| Title: | Ovine prion protein variant A(136)R(154)L(168)Q(171) increases resistance to experimental challenge with bovine spongiform encephalopathy agent |
| Journal: | J Gen Virol., 2006, 87(Pt 12); 3741-5 |
| Links: |
PubMed | Abstract | List all data
| Edit |
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