Release 56
(Apr 24, 2025)

QTL 13863 Description:

 Trait Information
Trait name: Scrapie susceptibility Vertebrate Trait Ontology: n/a
Reported name: scrapie susceptibility Product Trait Ontology: n/a
Symbol: SCRP Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:18
QTL Peak Location:130.4 (cM)
QTL Span:127.70-127.70 (cM)
68.0-68.0 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:
Analysis type:Association
Model tested:Mendelian
Test base:n/a
Threshold significance level:Significant
P_values0.04
Dominance effect:n/a
Additive effect:n/a
Associated Gene:HSP90AA1 (heat shock protein 90kDa alpha (cytosolic), class A member 1)
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Romanov sheep.
     Breeds associated:
    Design:Animals were genotyped for 22 polymorphisms in HSP90AA1 5' flanking region and intron 10 and analyzed for scrapie incubation period.
    Analysis:The general linear model procedure was used.
    Software:SAS
    Notes: 
    Links:Edit

     Reference
    Authors:Marcos-Carcavilla A, Moreno C, Serrano M, Laurent P, Cribiu EP, Andréoletti O, Ruesche J, Weisbecker JL, Calvo JH, Moazami-Gouda
    Affiliation:Dpto. de Mejora Genética Animal, INIA, 28040, Madrid, Spain; INRA, UMR1313, 78350 Jouy-en-Josas, France
    Title:Polymorphisms in the HSP90AA1 5' flanking region are associated with scrapie incubation period in sheep.
    Journal:Cell stress & chaperones, 2010, 15(4): 343-9
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:Incubation period
    User inputs on reference #19838832
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  • Cite this Data:

    Animal QTLdb: QTL13863 was published in 2010, and was curated into QTLdb on 2012-07-31. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:13863

     

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