| QTL Map Information |
|---|
| Chromosome: | 20 |
| QTL Peak Location: | 55.7 (cM) |
| QTL Span: | 50.41-50.61 (cM)
26.0-26.1 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | |
| Analysis type: | Association |
| Model tested: | Mendelian |
| Test base: | n/a |
| Threshold significance level: | Significant |
 |
P_values | 0.024 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | MHCII-DRB1 (MHC DR beta chain) |
| Cis/Trans acting type: |  |
| Links:
NCBI GeneDB | Edit |
Map view
|
| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
|---|
| Animals: | Animals were Latxa sheep. |
| Breeds associated:
|
| Design: | Animals were genotyped for 40 SNPs in DRB1 and analyzed for susceptibility to ovine pulmonary adenocarcinoma and Maedi-Visna virus. |
| Analysis: | A logistic regression model for allelic comparisons was applied for each disease. |
| Software: | SAS, STATXACT, R software |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Larruskain A, Minguijón E, García-Etxebarria K, Moreno B, Arostegui I, Juste RA, Jugo BM |
| Affiliation: | Genetics, Physical Anthropology and Animal Physiology Department, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Bilbao, Spain |
| Title: | MHC class II DRB1 gene polymorphism in the pathogenesis of Maedi-Visna and pulmonary adenocarcinoma viral diseases in sheep |
| Journal: | Immunogenetics, 2010, 62(2): 75-83 |
| Links: |
PubMed | Abstract | List all data
| Edit |
| Additional Information |
|---|
| Comments: | DRB1*0143 |
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