Release 56
(Apr 24, 2025)

QTL 15322 Description:

 Trait Information
Trait name: Scrapie susceptibility Vertebrate Trait Ontology: n/a
Reported name: scrapie susceptibility Product Trait Ontology: n/a
Symbol: SCRP Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:18
QTL Peak Location:130.8 (cM)
QTL Span:127.70-127.70 (cM)
68.0-68.0 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:
Analysis type:Association
Model tested:Mendelian
Test base:n/a
Threshold significance level:Significant
P_values0.0022
Dominance effect:n/a
Additive effect:n/a
Associated Gene:HSP90AA1 (heat shock protein 90kDa alpha (cytosolic), class A member 1)
Cis/Trans acting type:
Links:   Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Rasa Aragonesa sheep.
     Breeds associated:
    Design:Animals were genotyped for 8 SNPs in HSP90AA1 and analyzed for scrapie incidence.
    Analysis:Maximum likelihood variance analyses were performed.
    Software:CRIMAP, SAS
    Notes: 
    Links:Edit

     Reference
    Authors:Marcos-Carcavilla A, Calvo JH, Gonzalez C, Moazami-Goudarzi K, Laurent P, Bertaud M, Hayes H, Beattie AE, Serrano C, Lyahyai J,
    Affiliation:Departamento de Mejora Genética Animal, INIA, Ctra La Coruña Km 7.5, Madrid, Spain
    Title:Structural and functional analysis of the HSP90AA1 gene: distribution of polymorphisms among sheep with different responses to scrapie.
    Journal:Cell stress & chaperones, 2008, 13(1): 19-29
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:3' flanking region
    User inputs on reference #18347938
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  • Cite this Data:

    Animal QTLdb: QTL15322 was published in 2008, and was curated into QTLdb on 2012-07-31. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:15322

     

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